About our test
The cancer predisposition panel test we offer uses Next Generation Sequencing (NSG) to test a total of 92 genes. The analysis will look for those inherited mutations on specific genes which are known to increase a person’s risk of developing a certain type of cancer.
The cost of the complete cancer panel test is of XXXXXXX. The results for this test are ready in 6-9 weeks from the moment the samples are received at the laboratory.
Overall, it is estimated that somewhere between 5-10% of all cancers are hereditary in nature. Early detection is key to successful treatment! If you know you are genetically predisposed to certain cancers, you can regularly monitor your health, maintain recommended checkups and adopt measures to reduce your risk of developing cancer.
Who should consider genetic testing for cancer predisposition?
It is highly recommended that you speak to a doctor or genetic councilor to establish whether you need this test. There are 3 main criteria which should be met in order for genetic predisposition testing for cancer to be recommended:
- Individuals with a family history of cancer or a medical history that suggests the possibility of a familial type of cancer.
- Having genetic test results that can be meaningful and reliable. This entails having results that can clearly define whether a specific gene, associated with a certain type of cancer, is actually present.
- Receiving results that can help inform and guide a person’s medical care.
Sample collection for cancer testing
All we need to establish whether you carry certain genes associated with cancer is a sample of cheek cells which can be collected without any medical assistance whatsoever. We will provide our clients with a kit which will contain:
- The sterile mouth swab samples
- Consent forms
- Pre-addressed envelope
Mouth swabs need to be rubbed inside the mouth. The rubbing motion against the lining of the mouth causes exfoliated cheek cells to attach themselves to the swab. These are the cells that will get analyzed in the laboratory for all 92 cancer genes included in this genetic predisposition test panel.
Note: Results for this test must be sent directly to a health care professional such as a genetic councilor or oncologist. These individuals are highly trained and qualified to help you make sense of the results and interpret them. They can provide you with guidelines and valuable information regarding further tests, support you and describe any known factors that may increase or decrease your chances of developing the cancer/s highlighted in your results.
The full list of genes we test for can be found by clicking here.
Why not consult a genetic counsellor about your results?
Our genetic counsellor is ideal if you have any concerns about your DNA test results. They can understand and interpret all aspects of your DNA test results, helping you maximize your own wellbeing and that of your relative. Genetic counselling is ideal in cases where you opt for a clinical test or health test but you can also consult our counsellor for any other test including parentage testing, prenatal testing and relationship testing. Genetic counselling is available at an additional fee.
|Do all blood members in a family inherit a hereditary cancer-predisposing mutation?
|Do you offer other genetic tests?|
|If I don’t have a predisposition to a certain cancer, does that mean I will not get it?
|Should I test children?||
No, just because one or more members in a family carry gene mutations, it does not mean that all members of the family will carry that gene.
Yes, we offer a genetic health test which looks at your likelihood of developing 35 different diseases over the course of your life. The diseases tested fall into various categories including diseases of old age, autoimmune diseases and cardiovascular diseases.
This is actually a common misconception. Not having a hereditary gene which predisposes you to a certain type of cancer does not mean you cannot develop that cancer. Many cancers are due to what we call sporadic gene mutations and are not caused by an inherited gene. Lifestyle factors can play an important role in sporadic cancer (for example exposure to the sun, smoking etc).
This all depends on the type of cancer we are looking for – in cases of cancers that have a high incidence rate in children, cancer testing could be recommended. Most genetic councillors however, would generally advise against cancer testing in people under the age of 18. Individuals should be able to make their own choice as to whether they want to carry out such a test. Again, you need to speak to a genetic councillor or oncologist to determine whether you or anyone in your family should take this test.